PropFinderPropFinder Blog
LoginSign Up Free
AllMLBNBANFLNHLSoccerGolfMMATennis
MLB

Best MLB Home Run Props Today HR Picks for Tuesday, September 22

Jake Casso·September 22, 2026 at 5:10 PM UTC·Updated September 22, 2026 at 7:15 PM UTC·3 min read

I went through all 16 games on Tuesday, September 22nd to find the best home run matchups so you don’t have to. Using PropFinder’s data tools, I’ve identified a combination of vulnerable pitchers, strong hitter splits, and ballpark factors. Below are my top three MLB home run props and best home run picks for today’s slate.

Henry Bolte to hit a HR --- (+650, Fanatics)

Bolte is an A’s rookie with 11 home runs, and the platoon edge is the whole story: 7 of those 11 have come off left-handers. Against southpaws he hits .278 with a .476 slugging percentage and an .831 OPS, going deep once every 18 at-bats --- nearly double his overall rate. He draws lefty Yusei Kikuchi at home in Sacramento’s Sutter Health Park, a hitter-friendly run environment (1.10 park factor).

The model tags him at 17.5% to homer with a 96th-percentile tier score, backed by a 15.4% barrel rate and a 109.6 mph max exit velocity. Kikuchi’s fastball-slider mix leaves plenty of pitches to punish, and at +650 the price sits well above where the model values the bat.

Henry Bolte vs Yusei Kikuchi matchup breakdownHenry Bolte pitch-type and home run data

Jake Burger to hit a HR --- (+376, Novig)

Burger is the model’s favorite bat on the board at 28.1% to go deep. He already owns 16 home runs and a .183 ISO, but the split that matters is against lefties: .264 with a .505 slugging percentage, an .815 OPS and a homer every 18 at-bats, with the strikeouts cut to just 18%. He gets left-hander Sean Manaea at home in Globe Life Field.

Manaea is the target --- a 1.73 HR/9 starter the model flags as highly vulnerable --- and Burger’s 19.2% barrel rate is the strongest of tonight’s three picks. The ballpark plays a touch under neutral (0.94), but the matchup and raw power carry it. Novig’s +376 is the best number available across legal books.

Jake Burger vs Sean Manaea matchup breakdownJake Burger batted-ball history vs Manaea

Jordan Lawlar to hit a HR --- (+590, Novig)

Lawlar is the longshot swing, and the case is built on the pitcher and the park more than the bat. The Diamondbacks rookie heads into Coors Field --- the best home run park in baseball --- against Kyle Freeland, a left-hander the model grades as one of the most homer-prone starters on the slate (2.37 HR/9, a .605 opponent slugging percentage).

Lawlar’s own numbers against lefties are thin so far, so this is a projection play on environment: elite altitude, a pitcher who leaves the ball up, and a bat with a .187 ISO and a homer every 22 at-bats overall. At +590 it’s a worthwhile boom-or-bust leg to anchor the longshot side of the card.

Jordan Lawlar vs Kyle Freeland matchup breakdownJordan Lawlar exit velocity data

HR Prop Parlay

Combining the three legs into one home run parlay pays +20816. Odds are subject to change.

PropFinder My Picks home run parlay card

Affiliate disclosure: This page may contain affiliate links; we may earn a commission at no extra cost to you. Must be of legal age to wager. If you or someone you know has a gambling problem, support is available --- 1-800-GAMBLER.

Odds and lines were accurate at the time of publishing and are subject to change. Must be 21+ and physically located in a jurisdiction where wagering is legal. Gambling problem? Call 1-800-GAMBLER.

Share
J

Jake Casso

Jake is a Chicago native and lifelong sports enthusiast who brings energy, creativity, and expertise to the PropFinder team. He plays a key role in developing educational livestreams and producing YouTube content that helps sports bettors better understand betting markets, strategies, and data-driven insights.

Related reading

Best MLB Home Run Props Today HR Picks for Wednesday, September 16

Today's top three MLB home run props for Wednesday, September 16: Cam Smith, Riley Greene, and Juan Soto.

Sep 16, 2026

Best MLB Home Run Props Today HR Picks for Monday, September 15

Today's top three MLB home run props for Monday, September 15: Coby Mayo, Lazaro Montes, and Luis Garcia Jr.

Sep 15, 2026

Best MLB Home Run Props Today HR Picks for Sunday, September 14

Today's top three MLB home run props for Sunday, September 14: Hunter Goodman, Luis Campusano, and Pete Crow-Armstrong.

Sep 14, 2026
← Previous

Best MLB Home Run Props Today HR Picks for Wednesday, September 16

Find profitable props faster

PropFinder has all the tools to help you make smarter bets and find real edges with data-driven insights.

Try PropFinder Free
PropFinderPropFinder

The smarter way to find profitable sports betting props. Data-driven tools for serious bettors.

Product

  • Research Tools
  • Cheatsheets
  • Weather

Resources

  • Blog
  • Tutorials

Legal

  • Privacy Policy
  • Terms of Service
21+Gambling problem? Call 1-800-GAMBLER. Please bet responsibly.Responsible gaming resources

PropFinder provides data and research tools for informational and entertainment purposes only and does not accept or facilitate bets. Odds are subject to change. Check the rules in your jurisdiction.

© 2026 PropFinder. All rights reserved.